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Study Finds Prostate Cancer Test Misdiagnoses
A study published in the New England Journal of Medicine reports that the widely used prostate-specific antigen (PSA) test misses 65% of cancers in older males. Currently, the guidelines for reading the test results state that a PSA level of 4 or under is considered healthy, while a level from 4 to 10 means there is a 25% chance the patient has prostate cancer. Levels above 10 indicate that there is more than a 67% chance that cancer is present.
Dr. Rinaa Punglia of Harvard Medical School, who led the team of researchers in the study, found that 82% of men under 60 with prostate cancer initially tested at a PSA level below 4. The study's researchers recommended lowering the cut-off for a healthy reading to 2.6 in order to identify more cases of cancer that would otherwise be missed.
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